Fluorine compounds in anaesthesia (5) Examination of six heavily halogenated aliphatic compounds
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Genetic adaptation of bacteria to halogenated aliphatic compounds.
The bacterial degradation and detoxification of chlorinated xenobiotic compounds requires the production of enzymes that are capable of recognizing and converting compounds which do not occur at significant concentrations in nature. We have studied the catabolic route of 1,2-dichloroethane as an example of a pathway for the conversion of such a synthetic compound. In strains of Xanthobacter and...
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............................................................................................. vi JUSTIFICATION ........................................................................................ 1 METHODS ................................................................................................ 2 ..................................................................... RESULTS AND SIGNIF...
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A bacterium that is able to utilize a number of halogenated short-chain hydrocarbons and halogenated carboxylic acids as sole carbon source for growth was identified as a strain of Xanthobacter autotrophicus. The organism constitutively produces two different dehalogenases. One enzyme is specific for halogenated alkanes, whereas the other, which is more heat stable and has a higher pH optimum, ...
متن کاملMicrobial degradation of halogenated compounds.
Fried, J., Thomas, R. W. & Klingsberg, A. (1953) J. Amer. Chem. SOC. 75, 5764-5765 Gibson, D. T. (1971) Crit. Rev. Microbiol. 1, 199-223 Griffin, M. & Trudgill, P. W. (1972) Biochem. J. 129,595-603 Griffin, M. & Trudgill, P. W. (1976) Eur. J. Biochem. in the press Guilbert, C. C. & Chung, A. E. (1974)J. Biol. Chem. 249, 1026-1030 Guyer, M. & Hegeman, G. (1969) J. Bacteriol. 99, 906-907 Harrison...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1962
ISSN: 0003-2409
DOI: 10.1111/j.1365-2044.1962.tb13474.x